Name: 5-Fluoro-UR-144 and XLR11 [1-(5-Fluoro-pentyl)1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone
Type:
AKA: 5-Fluoro-UR-144, XLR-11, XLR11, synthetic cannabinoids
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
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IV. History
5-Fluoro-UR-144 and XLR-11 are synthetic cannabinoids developed in the early 2010s as part of research into novel psychoactive substances. They were designed to interact with cannabinoid receptors and mimic THC's effects. These compounds became popular in synthetic cannabis products, leading to widespread recreational use. Due to their potent psychoactive effects and potential health risks, they have been subjected to legal regulations in many countries. Their history reflects the challenges of managing new synthetic drugs and their impact on public health.
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V. Legal Information
5-Fluoro-UR-144 and XLR11 are synthetic cannabinoids with high abuse potential. They are controlled in the United States under Schedule I due to their psychoactive effects. Many other countries also regulate these substances to prevent misuse and safeguard public health. [Source: UNODC].
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
5-Fluoro-UR-144 and XLR11 are synthetic cannabinoids with potent psychoactive effects. They act as uppers, causing euphoria and altered perceptions. Short-term use can produce intense effects, while long-term health impacts are not well documented. Overdose risks include severe psychological effects and potential toxicity. Safe use is uncertain due to limited research. Recent studies focus on their potency and potential health effects. |
VII. Psychological Effects
5-Fluoro-UR-144 and XLR11 are synthetic cannabinoids with potent effects. They cause euphoria, altered perception, and anxiety. Immediate impacts include paranoia and cognitive impairment. Long-term use can lead to dependence, severe psychiatric disorders, and cognitive deficits. Recent research indicates higher risks of severe anxiety and psychotic episodes compared to natural cannabinoids.
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VIII. Culture
5-Fluoro-UR-144 and XLR11 are synthetic cannabinoids with psychoactive effects. Their cultural significance is related to their use in recreational settings and their potential for abuse. Media coverage often addresses the risks and effects of synthetic cannabinoids, including potential for overdose and addiction. These substances are used recreationally rather than medicinally and contribute to discussions about synthetic cannabinoids and drug regulation.
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